In pediatric patients 12 to 17 years of age, administer DUPIXENT under the supervision of an adult. The DUPIXENT pre-filled syringe is for use in adult and pediatric patients aged 6 months and older.Ī caregiver or patient 12 years of age and older may inject DUPIXENT using the pre-filled syringe or pre-filled pen. The DUPIXENT pre-filled pen is for use in adult and pediatric patients aged 12 years and older. Use Of Pre-filled Pen Or Pre-filled Syringe Provide proper training to patients and/or caregivers on the preparation and administration of DUPIXENT prior to use according to the “Instructions for Use”. See AnswerĭOSAGE AND ADMINISTRATION Important Administration InstructionsĭUPIXENT is administered by subcutaneous injection.ĭUPIXENT is intended for use under the guidance of a healthcare provider.
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QUESTION Eczema (also atopic eczema or atopic dermatitis) is a general medical term for many types of skin inflammation. Eosinophilic EsophagitisĭUPIXENT is indicated for the treatment of adult and pediatric patients aged 12 years and older, weighing at least 40 kg, with eosinophilic esophagitis (EoE). Chronic Rhinosinusitis With Nasal PolyposisĭUPIXENT is indicated as an add-on maintenance treatment in adult patients with inadequately controlled chronic rhinosinusitis with nasal polyposis (CRSwNP). Limitations Of UseĭUPIXENT is not indicated for the relief of acute bronchospasm or status asthmaticus.
AsthmaĭUPIXENT is indicated as an add-on maintenance treatment of adult and pediatric patients aged 6 years and older with moderate-to-severe asthma characterized by an eosinophilic phenotype or with oral corticosteroid dependent asthma. DUPIXENT can be used with or without topical corticosteroids.
Each pre-filled syringe delivers 300 mg dupilumab in 2 mL which also contains L-arginine hydrochloride (10.5 mg), L- histidine (6.2 mg), polysorbate 80 (4 mg), sodium acetate (2 mg), sucrose (100 mg), and water for injection, pH 5.9.ĭUPIXENT is indicated for the treatment of adult and pediatric patients aged 6 months and older with moderate-to-severe atopic dermatitis whose disease is not adequately controlled with topical prescription therapies or when those therapies are not advisable. The needle cap is not made with natural rubber latex. DUPIXENT is provided as a single-dose pre-filled syringe with needle shield in a 2.25 mL siliconized Type-1 clear glass syringe. Dupilumab has an approximate molecular weight of 147 kDa.ĭupilumab is produced by recombinant DNA technology in Chinese Hamster Ovary cell suspension culture.ĭUPIXENT (dupilumab) Injection is supplied as a sterile, preservative-free, clear to slightly opalescent, colorless to pale yellow solution for subcutaneous injection. DESCRIPTIONĭupilumab, an interleukin-4 receptor alpha antagonist, is a human monoclonal antibody of the IgG4 subclass that binds to the IL-4Rα subunit and inhibits IL-4 and IL-13 signaling. You may report side effects to FDA at 1-80. For more information, ask your doctor or pharmacist.Ĭall your doctor for medical advice about side effects. These are not all the possible side effects of Dupixent. Tell the doctor if you have any side effect that bothers you or that does not go away.
The most common side effects of Dupixent include: Get medical help right away, if you have any of the symptoms listed above. outward eyelid rotation (cicatrical extropion).What are the possible side effects of Dupixent?ĭupixent may cause serious side effects including: It is not known if Dupixent is safe and effective in children younger than 6 years of age. Dupixent may be used alone or with other medications.ĭupixent belongs to a class of drugs called Interleukin Inhibitors.
Find Lowest Prices on What is Dupixent and how is it used?ĭupixent is a prescription medicine used to treat the symptoms of Atopic Dermatitis and Moderate-to-Severe Asthma.
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